There are many active research projects accessing and applying shared ADNI data. Use the search above to find specific research focuses on the active ADNI investigations. This information is requested annually as a requirement for data access.
Principal Investigator | |
Principal Investigator's Name: | Jana Fehr |
Institution: | Hasso-Plattner-Institute |
Department: | Digital Health Centre |
Country: | |
Proposed Analysis: | We seek to investigate the transportability of algorithms predicting the diagnosis of Alzheimers using concepts from causal inference. Building up on the study of Piccininni et al. (https://doi.org/10.1186/s12874-020-01058-z) we will first draw a Directed-acyclic graph (DAG) including factors and their relationships determining AD onset. In a second stage we want to use ADNI data to estimate the distribution of factors, quantify of their relationships and use those for a predictive model. Next, we will simulate data from this scenario but change distribution of exogenous variables to mimic new population data and compute the predictive power of a diagnostic algorithm on this data and investgate the transportability of the model. |
Additional Investigators |